Sunday, April 12, 2009

Expression of many taste receptor genes in the same cell

Unlike olfactory system receptor cells, individual
taste receptor cells express multiple
T2R receptors. Up to ten T2R probes hybridize to
only a few cells, shown darkened (1). Doublelabel
fluorescent in-situ hybridization shows
that different receptor genes (2, T2R-3 in green
and T2R-7 in red, 3) are expressed in the same
taste receptor cell. The T2Rs confer high sensitivity
for bitter substances at low concentrations
but do not distinguish between them.

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